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Chemistry
5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course.
Acknowledgements
The materials for 5.33 reflect the work of many faculty members associated with this course over the years.
WARNING NOTICE:
The experiments described in these materials are potentially hazardous and require a h...
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Chemistry
This seminar will be a scientific exploration of the food we eat and enjoy. Each week we shall have a scientific edible experiment that will explore a specific food topic. This will be a hands-on seminar with mandatory attendance of at least 85%. Topics include, but are not limited to, what makes a good experiment, cheese making, joys of tofu, food biochemistry, the science of spice, what is taste?
This course is the second in a series of two courses in kitchen chemistry. The prerequisit to ...
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Chemistry
This course deals with the application of structure and theory to the study of organic reaction mechanisms: Stereochemical features including conformation and stereoelectronic effects; reaction dynamics, isotope effects and molecular orbital theory applied to pericyclic and photochemical reactions; and special reactive intermediates including carbenes, carbanions, and free radicals.
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Chemistry
This course deals with a more advanced treatment of the biochemical mechanisms that underlie biological processes. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes. Topics include macromolecular machines for energy and force transduction, regulation of biosynthetic and degradative pathways, and the structure and function of nucleic acids.
The tools section includes info...
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Chemistry
This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT.
Acknowledgements
The laboratory manual and materials for this course were prep...
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Chemistry
5.451 is a half-semester introduction to natural product biosynthetic pathways. The course covers the assembly of complex polyketide, peptide, terpene and alkaloid structures. Discussion topics include chemical and biochemical strategies used to elucidate natural product pathways.
This course features a full set of problem sets with solutions in the assignments section.
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Chemistry
This course in crystal structure refinement examines the practical aspects of crystal structure determination from data collection strategies to data reduction and basic and advanced refinement problems of organic and inorganic molecules.
This course features detailed lecture notes.
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Chemistry
5.32 involves more advanced experimental work than 5.310 or 5.311. The course emphasizes organic synthesis assisted by chiral catalysis, purification, and analysis of organic compounds employing such methods as IR, 1D and 2D NMR, UV spectroscopies and mass spectrometry, and thin layer and non-chiral and chiral gas chromatography. In 5.32, experiments also involve enzyme purification, characterization and assays, as well as molecular modeling in organic synthesis and in biochemical systems.
WAR...
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Chemistry
5.302 is a 3-unit course intended to provide freshmen with a stimulating and enjoyable "hands-on" experience with chemical phenomena. The aim of this course is to provide freshmen with an opportunity to get "up close and personal" with the chemical phenomena introduced in 5.111, 5.112 and 3.091. Interesting and dramatic experiments have been selected to illustrate and reinforce the concepts and principles introduced in the chemistry core lecture courses.
Acknowledgements
The laboratory manual ...
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Chemistry
5.311 is the first of a three-term laboratory subject sequence for chemistry majors. Experimental work emphasizes development of fundamental laboratory skills and techniques: volumetric and colorimetric analysis; nuclear magnetic resonance; preparation, purification, and characterization of chemical substances; and data analysis.
Acknowledgements
The experiments for 5.311 have evolved over a period of many years and include contributions from past instructors, course textbooks, and others aff...
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Chemistry
5.73 covers fundamental concepts of quantum mechanics: wave properties, uncertainty principles, Schrodinger equation, and operator and matrix methods. Basic applications of the following are discussed: one-dimensional potentials (harmonic oscillator), three-dimensional centrosymetric potentials (hydrogen atom), and angular momentum and spin. The course also examines approximation methods: WKB method, variational principle, and perturbation theory.
This course features comprehensive lecture no...
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Chemistry
5.73 covers fundamental concepts of quantum mechanics: wave properties, uncertainty principles, Schr dinger equation, and operator and matrix methods. Basic applications of the following are discussed: one-dimensional potentials (harmonic oscillator), three-dimensional centrosymmetric potentials (hydrogen atom), and angular momentum and spin. The course also examines approximation methods: variational principle and perturbation theory.
This course features a complete set of lecture notes.
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